Mecru Clinical Research Unit (MeCRU) is a unit which was established at Sefako Makgatho Health Sciences University from October 2005. The facility was established with the support of MRC through the South African AIDS Vaccine Initiative (SAAVI) and was officially opened by Minister of Health, Dr Aaron Motsoaledi, on the 3rd of June 2010. The Unit is administratively under the Department of Microbiological Pathology. It is managed by the leadership of a site principal investigator, supported by sub investigators, manager together with a board.
An important element of the administration of the work of the Unit is the Community advisory groups (CAG) established to maintain a strong link between the Unit and the community. This gives credence to the belief that all research needs to be of benefit to the communities in which it is conducted.
Read about current achievements http://www.prnewswire.com/news-releases/improving-the-effect-of-hiv-drugs-by-use-of-the-tat-vaccine-300281059.html
Electron Microscope Unit
As an Academic Support Unit, the Electron Microscope Unit provides a centralised research and high-resolution diagnostic support facility to all staff and postgraduate students of the Sefako Makgatho Health Sciences University, as well as external users. A new Variable Pressure Field Emission Scanning Electron Microscope with a cryo-attachment and X-Ray microanalysis is available for high-resolution imaging of research samples. Diagnostic and research support related to tissue samples are facilitated with our Transmission Electron Microscope. State-of-the-art equipment is available to support new innovative techniques for electron microscopical preparation and digital imaging. Further to this, a high-end research stereomicroscope and fluorescence microscope is also available for specific investigations. Please contact the Electron Microscope Unit directly at (012) 521-4334 to discuss your microscopy needs, as a vast range of samples can be viewed at high magnification to meet your research requirements.
Dr C Baker, Director of the Electron Microscope Unit with Mrs M Mogale, using the Leica HPM 100 High Pressure Freezer for cryofixation of tissue samples with liquid nitrogen. This equipment was acquired by means of a grant award from the National Research Foundation in partnership with the Department of Science and Technology.
Dr C Baker (Director: Electron Microscope Unit) operating the Zeiss Supra 55 VP Field Emission Scanning Electron Microscope for which we received a grant award of R5.6 million from the National Research Foundation in partnership with the Department of Science and Technology. Many researchers at the University as well as external clients make use of this equipment to obtain high magnification images of their research samples. X-Ray microanalysis and cryotechniques can also be performed using specialised attachments on this instrument.
MRC Diarrhoeal Pathogens Unit
The MRC Diarrhoeal Pathogens Research Unit (DPRU) was established at the former MEDUNSA in April 1996, and was the first MRC unit to be founded at a previously disadvantaged institution. The DPRU was founded on the principle that it will address a national and continental disease that was under-researched in Africa. Diarrhoeal diseases remain a leading cause of mortality among infants and young children in Africa. It is estimated that diarrhoeal disease is the primary cause of death in children younger than 5 years, leading to about 160 – 200 deaths per day in South Africa.
Rota unit:The lady in the photo is loading a gel to allow detection of PCR
WHO Rotavirus Regional Reference Laboratory core functions
Rotavirus epidemiology and genomics in Africa
Microbiome and metagenomics of the gut
Epidemiology and surveillance studies of diarrhoeal pathogens
The South African Vaccination and Immunisation Centre (SAVIC) were established in 2003, as a network of partners in the field of vaccination and immunisation. SAVIC is a Public Private Academic alliance between the National Department of Health (NDoH), the vaccine industry, academic institutions and other stakeholders, with its activities undertaken in close collaboration with the NDoH, Network for Education and Support in Immunisation (NESI, based at the University of Antwerp), the World Health Organization (WHO) and its partners.
The strategic operational areas of SAVIC focus on three issues:
Education and Training
SAVIC, in collaboration with NDoH, the National Advisory Group on Immunisation (NAGI) and partners from the vaccine industry initiated the development of an online Higher Certificate (HCert) Vaccinology Programme geared towards the training of in-service HCWs who work in EPI-SA and private sector clinics that offer childhood vaccination services.
SAVIC research is based around three key areas: behavioral and social issues; epidemiology of VPDs; and health systems management and policy.
Technical Support and Advocacy
The main objective is to allow rapid dissemination of up-to-date information on vaccines and immunisation at global, regional and national level.