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Medicine Latest Research Output: 2023

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Research Ethics Committee

The National Health Act 61 of 2003 requires that all health research in South Africa must be reviewed and approved by an ethics committee that is registered with the National Health Research Ethics Council (NHREC) . Our ethics review and processes are guided by the National Department of Health ‘Ethics in Health Research: Principles, Processes and Structures (2015), 2nd Edition’

SCHOOL OF MEDICINE

  • Geel, J, Hendricks, M, Goga, Y, Neethling, B, Netshituni, V, Mathew, R, Vermeulen, J, van Zyl, A, Omar, F, du Plessis, J, du Plessis, L, Madzhia, E, Ngcana, T, Naidoo, T, Louw, L, Ballot, DE & Metzger, ML 2023, ‘SACCSG HL-2018. Barriers and enablers of a harmonized treatment protocol for childhood and adolescent Hodgkin lymphoma in South Africa’, Pediatric Hematology and Oncology, vol. 40, no. 3, pp. 300-313. https://doi.org/10.1080/08880018.2022.2162651 J108
  • Zimmer, VA, Oettlé, A, Hoffmannc, J, Thackeray, JF, Zipfel, B & Braga, J 2023, ‘Revisiting mandibular symphyseal shape in juvenile early hominins and modern humans using a deformation-based approach’, Folia Primatologica, vol. 443, no. 7109. https://doi.org/10.1163/14219980-bja10014 J531
  • Lentoor, AG, Mdluli, T & Maepa, MP 2023, ‘‘I asked myself why I was having this difficult child’: Care Burden Experiences of Black African Mothers Raising A Child with Autistic Spectrum Disorder’, Open Public Health Journal, vol. 16, no. 1, e187494452306234. https://doi.org/10.2174/18749445-v16-230726-2023-25 J304
  • Semenya, CN, Golele, SS & Mabuza, LH 2023, ‘An evaluation of the use of external fixator in the management of open tibial shaft fractures at a tertiary hospital in pretoria, south africa’, Open Public Health Journal, vol. 16, e187494452302221. https://doi.org/10.2174/18749445-v16-e230418-2022-91 J65
  • Calvin Khaba, M, Jacob Koloi, S & Orecious Sadiki, T 2023, ‘Continued diagnostic challenges of central nervous system tuberculoma in the 21st century. A clinicoradiological and pathological case series’, Clinical Infection in Practice, vol. 20, 100238. https://doi.org/10.1016/j.clinpr.2023.100238 J169
  • Wei, P, Cazenave, M, Zhao, Y & Xing, S 2023, ‘Structural properties of the Late Pleistocene Liujiang femoral diaphyses from southern China’, Journal of Human Evolution, vol. 183, 103424. https://doi.org/10.1016/j.jhevol.2023.103424 J570
  • Dlamini, GF & Ndou, R 2023, ‘Osteoblastogenesis and osteolysis in the Zucker Diabetic Sprague Dawley rat humerus head’, Anatomy and Cell Biology, vol. 56, no. 4, pp. 552-561. https://doi.org/10.5115/ACB.23.166 J447
  • van der Walt, S., Hammer, N., & Prigge, L. (2023). Comparison Between the Parietal Foramina Observed in Samples of African and European Population Groups. International Journal of Morphology, 41(2), 634-639. https://doi.org/10.4067/S0717-95022023000200634 J158
  • Thomas, E., Oettlé, A.C. and Becker, P.J., 2023. Supernumerary teeth in a sample of South African dental patients. South African Dental Journal, 78(2), pp.74-81 J576
  • Marapo L; Seopa P; Mashamba TJ; Matsela L; Kekana T. Perimortem Caesarean Section Performed on a mother with Terminal Bilateral Breast Cancer. O&G Forum 2023; 33: 40-42. https://hdl.handle.net/10520/ejc-medog_v33_n1_a7 J459
  • Motsepe TA, Machete TA, Ziqubu N. Adult intussusception in the era of HIV/AIDS: A case report. S Afr J Infect Dis. 2023;38(1), a534. https://doi.org/10.4102/sajid.v38i1.534 J49
  • Mujuru, TN, Mahlangu, NP, Ngwetjana, SJ, Bekker, LC & Tanyanyiwa, DM 2023, ‘The impact of lockdown measures during the SARS-CoV-2 pandemic on the management of diabetes in a Northern Gauteng Region of South Africa’, Pan African Medical Journal, vol. 45, pp. 129. https://doi.org/10.11604/pamj.2023.45.129.39255 J601
  • Pandelani, FF, Nyalunga, SLN, Mogotsi, MM & Mkhatshwa, VB 2023, ‘Chronic pain: its impact on the quality of life and gender’, Frontiers in Pain Research, vol. 4, 1253460. https://doi.org/10.3389/fpain.2023.1253460 J143
  • Nzaumvila, DK, Mash, R & Helliwell, T 2023, ‘Exploring the perspectives of community members on use of Nyaope in Tshwane, South Africa’, South African Family Practice, vol. 65, no. 1, a5715. https://doi.org/10.4102/safp.v65i1.5715 J252
  • Mokoena, TP, Swart, HC, Nhlapo, TA, Mofokeng, SJ, Malevu, TD, Mhlongo, MR & Motaung, DE 2023, ‘Influence of exposure time and bias voltage on the response kinetics of toluene vapour on Ho3+-doped NiO chemiresistive sensors: Yellow-emitter nanophosphors’, Inorganic Chemistry Communication, vol. 158, 111378. https://doi.org/10.1016/j.inoche.2023.111378 J333
  • Nkwinka V. Dochez C, Duclos P, MacDonald N, Steffen C, Lambert PH; Global Vaccinology Training Collaborative. Advanced vaccinology training globally: Update and impact of the COVID-19 crisis. Vaccine. 2022 Sep 16;40(39):5683-5690. doi: 10.1016/j.vaccine.2022.08.029. Epub 2022 Aug 22. PMID: 36030127; PMCID: PMC9393177 J50
  • Geel, J, van Zyl, A, Plessis, JD, Hendricks, M, Goga, Y, Carr, A, Neethling, B, Hramyka, A, Omar, F, Mathew, R, Louw, L, Naidoo, T, Ngcana, T, Schickerling, T, Netshituni, V, Madzhia, E, du Plessis, L, Kelsey, T, Ballot, DE & Metzger, ML 2023, ‘Improved survival of children and adolescents with classical Hodgkin lymphoma treated on a harmonised protocol in South Africa’, Pediatric Blood and Cancer. https://doi.org/10.1002/pbc.30712 J320
  • Jiang, J, Soh, PXY, Mutambirwa, SBA, Bornman, MSR, Haiman, CA, Hayes, VM & Jaratlerdsiri, W 2023, ‘ANO7 African-ancestral genomic diversity and advanced prostate cancer’, Prostate Cancer and Prostatic Diseases. https://doi.org/10.1038/s41391-023-00722-x J53
  • Swanepoel, HF, Matthews, HS, Claes, P, Vandermeulen, D & Oettlé, AC 2023, ‘A statistical shape model for estimating missing soft tissues of the face in a black South African population’, Journal of Prosthodontics. https://doi.org/10.1111/jopr.13746 J37
  • Maepa, M.P. and Maine L. (2023). Interaction of gender and parenting styles on risk-taking and self-harm behaviour among university students in a semi-urban area in South Africa. Gender and Behaviour, https://hdl.handle.net/10520/ejc-genbeh_v21_n2_a7 J339
  • Ramose M 2023. Race is an indivisible singular but practice insists it is a frangible plural. Critical Philosophy of Race, 11(2). https://doi.org/10.5325/critphilrace.11.2.0264 J517
  • Jere, KC, Chibwe, I, Chaima, D, Kasambala, W, Mhango, C, Bitilinyu-Bangoh, J, Mvula, B, Kipandula, W, Kamng’Ona, AW, Steele, AD, Chauma-Mwale, A, Hungerford, D, Kagoli, M, Nyaga, MM, French, N, Dube, Q, Cunliffe, NA, Msefula, CL & Chaguza, C 2023, ‘Draft genomes of Aeromonas caviae from patients with cholera-like illness during the 2022-2023 cholera outbreak in Malawi’, Microbiology Resource Announcements, vol. 12, no. 10. https://doi.org/10.1128/MRA.00580-23 J209
  • Mabuza, LH & Moshabela, M 2023, ‘What do medical students and their clinical preceptors understand by primary health care in South Africa? A qualitative study’, BMC Medical Education, vol. 23, no. 1, 785. https://doi.org/10.1186/s12909-023-04751-x J649
  • GERMS-SA: Nchabeleng M 2023, ‘Candida auris Clinical Isolates Associated with Outbreak in Neonatal Unit of Tertiary Academic Hospital, South Africa’, Emerging Infectious Diseases, vol. 29, no. 10, pp. 2044-2053. https://doi.org/10.3201/eid2910.230181 J130
  • Zondi N; Pilloy WJ; Ntuli TS; Mutambirwa S & Nyakale NE The effectiveness of radionuclide scintigraphy in confirming testicular torsion at delayed presentation. Translational Andrology and Urology, 12(10):1550-1560 | https://dx.doi.org/10.21037/tau-23-116 J55 J594
  • Keetile N; Osuch E; Lentoor AG & Rasakanya T Association of Circulating Levels of Inflammatory Cytokines and Chemotherapy-Associated Subjective Cognitive Impairmenti n a South African Cohort of Breast Cancer Patients. Neuroscience, 4,296–304. https://doi.org/10.3390/ neurosci4040024 J103
  • GARFIELD-AF Investigators (Koto MZ) GARFIELD-AF: risk profiles, treatment patterns and 2-year outcomes in patients with atrial fibrillation in Germany, Austria and Switzerland (DACH) compared to 32 countries in other regions worldwide. Clinical Research in Cardiology, 112, 571-771. J275
  • Richards, GA, McDonald, M, Gray, CL, de Waal, P, Friedman, R, Hockman, M, Karabus, SJ, Lodder, CM, Mabelane, T, Mosito, SM, Nanan, A, Peter, JG, Quitter, THC, Seedat, R, van den Berg, S, van Niekerk, A, Vardas, E & Feldman, C 2023, ‘Allergic rhinitis: Review of the diagnosis and management: South African Allergic Rhinitis Working Group’, South African Family Practice, vol. 65, no. 1, a5806. https://doi.org/10.4102/safp.v65i1.5806 J58
  • Mpinda, B, Kabogo, CD, Yoko, JLM & Tumbo, J 2023, ‘Knowledge, attitudes, and practices of chronic disease patients in Bojanala towards COVID-19’, South African Family Practice, vol. 65, no. 1, a5763. https://doi.org/10.4102/safp.v65i1.5763 J360
  • Maroga, N, Mokoena, T, Ledibane, N, Musekiwa, A, Bida, M, Kgomo, M & Lebelo, R 2023, ‘Profile of human papillomavirus genotypes in breast and oesophageal cancer patients in Pretoria, South Africa’, South African Medical Journal, vol. 113, no. 7, pp. 49-54. https://doi.org/10.7196/SAMJ.2023.v113i7.560 J494
  • Ndou, R, Bello, NK, Perry, V & Pillay, D 2023, ‘Distal tibial trabecular morphometry in a Sprague Dawley rat model of fetal alcohol syndrome: a micro focus X-ray computed tomography case-control study’, Pan African Medical Journal, vol. 46, 35. https://doi.org/10.11604/pamj.2023.46.35.37151 J205
  • Global Andrology Forum 2023, ‘Does Varicocele Repair Improve Conventional Semen Parameters? A Meta-Analytic Study of Before-After Data’, World Journal of Men’s Health, vol. 41. https://doi.org/10.5534/wjmh.230034 J207
  • Okafor, UE & Hlabyago, KE 2023, ‘Knowledge, Attitude, and Practices of Type 2 Diabetic Patients Regarding Obesity at Odi District Hospital, Tshwane District, South Africa’, Open Public Health Journal, vol. 16, no. 1, e187494452309180. https://doi.org/10.2174/0118749445252145230920112100 J357
  • Gheybi, K, Mmekwa, N, Lebelo, MT, Patrick, SM, Campbell, R, Nenzhelele, M, Soh, PXY, Obida, M, Loda, M, Shirindi, J, Butler, EN, Mutambirwa, SBA, Bornman, MSR & Hayes, VM 2023, ‘Linking African ancestral substructure to prostate cancer health disparities’, Scientific Reports, vol. 13, no. 1, 20909. https://doi.org/10.1038/s41598-023-47993-x J367
  • Madela, SLM, Harriman, NW, Sewpaul, R, Mbewu, AD, Williams, DR, Sifunda, S, Manyaapelo, T, Nyembezi, A & Reddy, SP 2023, ‘Area-level deprivation and individual-level socioeconomic correlates of the diabetes care cascade among black south africans in uMgungundlovu, KwaZulu-Natal, South Africa’, PLoS ONE, vol. 18, no. 12 December, e0293250. https://doi.org/10.1371/journal.pone.0293250 J94
  • Soh, PXY, Mmekwa, N, Petersen, DC, Gheybi, K, van Zyl, S, Jiang, J, Patrick, SM, Campbell, R, Jaratlerdseri, W, Mutambirwa, SBA, Bornman, MSR & Hayes, VM 2023, ‘Prostate cancer genetic risk and associated aggressive disease in men of African ancestry’, Nature Communications, vol. 14, no. 1, 8037. https://doi.org/10.1038/s41467-023-43726-w J501
  • Potgieter, RL, Mwangi, PN, Mogotsi, MT, Uwimana, J, Mutesa, L, Muganga, N, Murenzi, D, Tusiyenge, L, Seheri, ML, Steele, AD, Mwenda, JM & Nyaga, MM 2023, ‘Genomic Analysis of Rwandan G9P[8] Rotavirus Strains Pre- and Post-RotaTeq® Vaccine Reveals Significant Distinct Sub-Clustering in a Post-Vaccination Cohort’, Viruses, vol. 15, no. 12, 2321. https://doi.org/10.3390/v15122321 J82
  • Ndlovu, TM & van Wyk, JPH 2023, ‘Saccharification of Various Wastepaper Materials by Cellulase from Brown Garden Snail (Cornu aspersum) at Different Incubation pH Values’, Nature Environment and Pollution Technology, vol. 22, no. 4, pp. 2153-2162. https://doi.org/10.46488/NEPT.2023.v22i04.041 J535
  • Ramashia, M, Phofa, TD, Nkawane, GM, Nogbou, ND, Bolukaoto, JY, Nchabeleng, M & Musyoki, AM 2023, ‘Investigation of carbapenem-resistant Enterobacterales isolates at a tertiary laboratory in Pretoria, South Africa’, Acta Microbiologica et Immunologica Hungarica. https://doi.org/10.1556/030.2023.02157 J343
  • Tumbo JM; Govender I & Nzaumvila DK After action review of the COVID-19 pandemic response in North West Province, South Africa. Southern African Journal of Infectious Diseases, 38(1). 1-6 J54
  • Maphiri AM & Bongongo T Profile of Women Seeking an Intra-uterine Contraceptive Device at a Community Health Centre in Pretoria, South Africa. Open Public Health Journal, 16, http://dx.doi.org/10.2174/18749445-v16-e230320-2022-143 J496
  • Glasbey, J., Trout, I., Adeyeye, V., Ademuyiwa, A., Adisa, A., Bhatt, A., Biccard, B., Brocklehurst, P., Chakrabortee, S., Allen Ingabire, J. D. L. C., Dossou, F. M., Durán, I., Dutta, R., Ghosh, D., Gyamfi, F., Hardy, P., Hyman, G., Jain, R., Kadir, B., … Escobar, E. G. (2023). Use of Telemedicine for Postdischarge Assessment of the Surgical Wound: International Cohort Study, and Systematic Review with Meta-analysis. Annals of Surgery, 277(6), E1331-E1347. https://doi.org/10.1097/SLA.0000000000005506 J642
  • Bruno MJ, Beyna T, Carr-Locke D, Chahal P, Costamagna G, Devereaux B, Giovannini M, Goenka MK, Khor C, Lau J, May G, Muthusamy VR, Patel S, Petersen BT, Pleskow DK, Raijman I, Reddy DN, Repici A, Ross AS, Sejpal DV, Sherman S, Siddiqui UD, Ziady C, Peetermans JA, Rousseau MJ, Slivka A; EXALT Single-use Duodenoscope Study Group. Global prospective case series of ERCPs using a single-use duodenoscope. Endoscopy, 55(12), 1103-1114. 1055/a-2131-7180.Epub 2023 Jul 18. J281
  • Magwira CA; Ndwamato N; Selabe SG & Seheri LM Lewis a-b- histo-blood group antigen phenotype is predictive of severe COVID-19 in the black South African population group. Glycobiology, 2023. https://doi.org/10.1093/glycob/cwad090 J365
  • NIHR Global Health Research Unit on Global Surgery, GlobalSurg Collaborative, NIHR Global Health Research Unit on Global Surgery Writing committee, GlobalSurg Collaborative writing group, GlobalSurg Collaborative patient representatives, Protocol development, GlobalSurg Collaborative national leads & GlobalSurg Collaborative protocol translators 2023, ‘Exploring the cost-effectiveness of high versus low perioperative fraction of inspired oxygen in the prevention of surgical site infections among abdominal surgery patients in three low- and middle-income countries’, BJA Open, vol. 7, 100207. https://doi.org/10.1016/j.bjao.2023.100207 J250
  • Ras T; Jenkins LS; Lazarus C; van Rensburg JJ; Cooke R; Senkubuge F; Dlova AN; Singaram V; Daitz E; Buch E; Thompson-Green L & Burch V 2023. We just don’t have the resources”: Supervisor perspectives on introducing workplace-based assessments into medical specialist training in South Africa. BMC Medical Education, 23, 832. https://doi.org/10.1186/s12909-023-04840-x J648
  • Murphy, SD, Nair, A, Kaswa, R, Govender, I & Von Pressentin, K 2023, ‘Guiding the emerging primary care researcher: A report of research capacity-building workshop’, South African family practice : official journal of the South African Academy of Family Practice/Primary Care, vol. 65, no. 1, pp. e1-e5. https://doi.org/10.4102/safp.v65i1.5769 J286
  • Human-Baron R; Tshabalala Z & van der Walt S Relation of the obturator nerve to Selected Perineal Surgical Procedures in a South African Population. Translational Research in Anatomy, 4(3), 127-134. J524
  • Mabotja R & Nganase TR Media influence on the body image of black women in a South African township. Gender & Behaviour 21,3. J372
  • Ngoato MH; Amponsah-Dacosta E; Blose N; Selabe SG; Msibi TL; Motswaledi MH & Musyoki AM Hepatitis B virus infection in patients presenting for immunosuppressive cancer therapy with and without underlying HIV infection. Frontiers in Virology, 3:1160078. https://doi.org/10.3389/fviro.2023.1160078 J291
  • Musonda JS; Sodo PP; Ayo-Yusuf O; Reji E; Musonda J; Mabuza LH; Ndimande JV; Akii J & Omole OB 2022. Cervical cancer screening in a population of black South African women with high HIV prevalence: A cross-sectional study. PLOS Global Public Health, 2,11. https://doi.org/10.1371/journal.pgph.0001249 J135
  • Khaba, M. C., & Dube, N. A. (2023). Clinicopathological report on epidermoid cysts of the brain: A case series and literature review from an African perspective. International Journal of Surgery Case Reports, 105, [107969]. https://doi.org/10.1016/j.ijscr.2023.107969
  • Lokotola, C. L., Mash, R., Naidoo, K., Mubangizi, V., Mofolo, N., & Schwerdtle, P. N. (2023). Climate change and primary health care in Africa: A scoping review. Journal of Climate Change and Health, 11, [100229]. https://doi.org/10.1016/j.joclim.2023.100229
  • Lentoor, AG 2023, ‘Cognitive and neural mechanisms underlying false memories: misinformation, distortion or erroneous configuration?. AIMS Neuroscience, vol. 10, no. 3, pp. 255-266.
  • Nyakale NE; Aldous C; Gutta AA; Khuzwayo X; Harry L & Sathekge MM 2023. Emerging theragnostic radionuclide applications for hepatocellular carcinoma. Frontiers in Nuclear Medicine, 2023. https://doi.org/10.3389/fnume.2023.1210982
  • Pheeha, SM, Tamuzi, JL, Chale-Matsau, B, Manda, S & Nyasulu, PS 2023, ‘A Scoping Review Evaluating the Current State of Gut Microbiota Research in Africa’, Microorganisms, vol. 11, no. 8, 2118. https://doi.org/10.3390/microorganisms11082118
  • Luvhengo, T. E., Bombil, I., Mokhtari, A., Moeng, M. S., Demetriou, D., Sanders, C., & Dlamini, Z. (2023). Multi-Omics and Management of Follicular Carcinoma of the Thyroid. Biomedicines, 11(4), [1217]. https://doi.org/10.3390/biomedicines11041217
  • Steegen, K., van Zyl, G. U., Claassen, M., Khan, A., Pillay, M., Govender, S., Bester, P. A., van Straaten, J. M., Kana, V., Cutler, E., Kalimashe, M. N., Lebelo, R. L., Moloi, M. B. H., & Hans, L. (2023). Advancing HIV Drug Resistance Technologies and Strategies: Insights from South Africa’s Experience and Future Directions for Resource-Limited Settings. Diagnostics, 13(13), [2209]. https://doi.org/10.3390/diagnostics13132209
  • Nyakale, N., Filippi, L., Aldous, C., & Sathekge, M. (2023). Update on PET Radiopharmaceuticals for Imaging Hepatocellular Carcinoma. Cancers, 15(7), [1975]. https://doi.org/10.3390/cancers15071975
  • Mabelane, T, Masekela, R, Dandara, C & Hadebe, S 2023, ‘Immunogenetics and pharmacogenetics of allergic asthma in Africa’, Frontiers in Allergy, vol. 4, 1165311. https://doi.org/10.3389/falgy.2023.1165311

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