Nondumiso Nkosi, a Master’s student in Medical Virology at Sefako Makgatho Health Sciences University (SMU), is making waves in biomedical innovation with a pioneering diagnostic assay for Hepatitis B. Developed in collaboration with Nagoya City University Hospital in Japan, her assay addresses a long-standing gap in accessible and efficient Hepatitis B diagnosis—particularly in regions where the disease is most prevalent.
The innovation holds immense promise for transforming public health outcomes in Africa. With millions affected by chronic Hepatitis B Virus (HBV) infections that often lead to liver disease, cirrhosis, or hepatocellular carcinoma, early diagnosis is critical. Nkosi’s diagnostic tool is designed for low-resource settings, offering a potentially life-saving solution where conventional diagnostic infrastructure is either limited or absent.
Her work has already earned national attention. In 2023, Nkosi presented the innovation at the Bio Africa Convention, where she was awarded runner-up in the innovation showcase. “That moment changed everything for me,” Nkosi reflects. “It made me realise the magnitude and potential impact of my work.”
With the mentorship of Dr Omphile Simani, and support from the SMU Technology Transfer Office (TTO), Nkosi’s innovation is now on the path toward commercialisation. “We are working with Nkosi and Simani to identify industry partners for scaling the assay,” says Mohlatlego Sebola of the TTO. The Office has also played a key role in securing intellectual property protection for her work, positioning her as a rising figure in South Africa’s intellectual property landscape.
SMU Vice-Chancellor, Professor Tandi Matsha-Erasmus, underscores the broader significance: “Our commitment at SMU is clear—we nurture innovation, excellence, and community service. Nkosi’s work is a shining example of this mission in action.”
But Nkosi’s story begins far from the laboratories and conferences. Raised by a single mother in Mpumalanga, she speaks openly about the challenges that shaped her. “My mother taught me strength, resilience and the value of education—no matter the odds,” she shares. “Those lessons carried me from the classroom, where I first discovered biology, to the lab, where I found my passion for medical virology.”
Navigating the complex world of science as a young woman, Nkosi faced the familiar struggle of balancing multiple roles. “Women are often expected to be everything at once—caregivers, professionals, daughters, partners, scholars,” she says. “At times, I felt pulled in every direction, but it was in those moments that my purpose became clear.”
Her determination culminated in a patented innovation, a rare and remarkable achievement for a young scientist. “To have my name on a patent is more than professional validation; it’s a statement that women belong at the forefront of scientific discovery.”
Nkosi’s journey is far from over, but her message is already resonating with many. “Your background doesn’t define your limits,” she says to young women pursuing careers in science. “You belong. Your resilience and your voice matter.”
By Dimakatso Modise
