by Lorato | Jul 9, 2025 | All News, Alumni, SMU Media, Student Media
At Sefako Makgatho Health Sciences University (SMU), leadership is more than a skill — it is a core value nurtured through rigorous clinical training, social accountability, and ethical governance. One shining example is Dr Siqiniseko Ntuli (36), who in January 2025 was appointed Chief Executive Officer (CEO) of Dannhauser Hospital in KwaZulu-Natal’s Amajuba District. His journey from rural KwaNongoma to the helm of a district hospital exemplifies SMU’s mission: to produce capable, compassionate leaders who transform systems and uplift communities. “It’s both exciting and terrifying,” Ntuli reflects. “Leading in these financially unstable times is a challenge, but it’s a calling I’m ready for — and one I approach with boldness.”
Raised in Ulundi in a humble home, Ntuli credits his father for instilling the belief that education could change not only his future but the fate of his community. “Even when the path seemed uncertain, I held on to that belief,” he recalls.
His path to leadership began at SMU, where he pursued medicine with a passion for clinical excellence. Although he didn’t initially set out to manage a hospital, his relentless pursuit of quality care and service excellence naturally positioned him for leadership. “I’ve always believed in doing my best. Leadership followed that commitment.”
After qualifying, he completed his internship within the Pietermaritzburg complex, gaining hands-on experience at Grey’s, Harry Gwala (formerly Edendale), and Northdale hospitals. It was here that his passion for district-level healthcare emerged. “Primary healthcare is the heartbeat of our system,” he says.
His community service at Ceza Hospital and later his post at Dannhauser Community Health Centre reinforced that passion. He eventually returned to Ceza Hospital as Medical Manager and Acting CEO, helping to stabilise operations in the face of major challenges. “We kept the hospital afloat and ensured that patients continued to receive quality care,” he says.
Now at the helm of Dannhauser Hospital, Ntuli is focused on improving access to healthcare, enhancing holistic services, and promoting preventative care. “We need to build a culture of health education and strengthen community participation. Health champions must emerge from within the communities we serve.”
Despite his executive role, Ntuli stays connected to the clinical side. Mornings are reserved for academic rounds and patient care, while evenings are dedicated to continuing education. “I never want to lose touch with medicine,” he says.
His leadership strategy is built on transparency, inclusive staffing, performance monitoring, and constant feedback. “We must create workspaces where individuals and teams thrive — that’s the foundation of quality service.”
Ntuli also emphasises the need for a culture shift. “Healthcare is more than a job — it’s a calling. We must cultivate passion, professionalism, and purpose.”
He attributes much of his leadership development to SMU’s bedside teaching model and Ubuntu-centred mentorship from esteemed figures like Prof Honey Mabuza and Prof Zach Koto. “You represent your university in how you work and how you lead,” he says.
To aspiring leaders, he offers timeless advice: “Be a great follower first. Respect those around you. Work hard, stay curious, and remain humble. That mindset will always take you far.”
Even with his demanding role, Ntuli stays grounded through prayer, reading, and time with family. “I always say I’ll join a gym — maybe one day,” he laughs. “But what keeps me grounded is seeing others make a difference.”
Looking ahead, Ntuli hopes to build leadership pipelines, formalise student placements, and forge deeper partnerships between SMU and healthcare institutions. “Hospitals must become academic allies. Research informs policy, and education drives equity.”
To young professionals navigating the weight of responsibility, he offers heartfelt reassurance: “You’re on the right path. Don’t give up. Rest if you must, reflect, and rise”.
Ntuli’s journey is a striking reflection of what SMU stands for: excellence in leadership, integrity in service, and courage in governance. Through his visionary yet grounded approach, he affirms SMU’s status as a national beacon for developing leaders who not only manage systems but transform them, with skill, purpose, and heart.
By Tumelo Moila
by Lorato | Jun 25, 2025 | Accolades and Achievements, All News, Alumni, SMU Media, Student Media
At the heart of SMU’s research strategy lies a commitment to interdisciplinary collaboration, knowledge generation, and technology transfer. By fostering innovation and expanding its research capacity, the university aims to play a pivotal role in addressing South Africa’s pressing healthcare challenges — from infectious diseases to mental health and non-communicable conditions.
A prime example of this ambition is the School of Pharmacy’s recent achievement: securing its second provisional patent. Dr Bwalya Witika, a senior lecturer in Pharmaceutics and his postdoctoral fellow, Dr Jean Ngilirabanga, who joined him in 2023, successfully filed a patent titled “Eutectic Compositions”, with the priority date of 9 June 2025. Their work explores novel drug delivery mechanisms by combining compounds to lower melting points, enhancing the efficacy and tolerability of treatments such as nonsteroidal anti-inflammatory drugs (NSAIDs). This breakthrough reaffirms the school’s growing reputation for pharmaceutical innovation and research excellence.
Eutectic compositions are mixtures of substances that, when combined, melt at a temperature lower than either of the individual components. In pharmaceutical science, this characteristic is highly valuable for improving drug solubility, stability and delivery, two critical challenges in modern medicine. Witika traced the origins of this research back to 2022, inspired by the urgent need for safer pain management alternatives during the global opioid crisis. “NSAIDs weren’t enough, and opioids came with long-term risks. I wondered—what if we enhanced NSAIDs with something like chilli?” he explained, referring to Nonivamide, a compound structurally related to capsaicin.
The research process involved formulating innovative drug combinations that provided synergistic pain relief. Despite the scientific and administrative challenges, the work culminated in a promising invention that could reshape pain treatment approaches. While the research was conducted internally at SMU, Witika confirmed that discussions with potential industry partners are already underway. “For now, it’s been in-house, but the potential for wider collaboration is significant,” he said.
Filing a provisional patent provides legal protection while allowing further refinement of the invention. Witika praised SMU’s Technology Transfer Office (TTO) for its vital support throughout the process. “TTO Liaison Officer Pontsho Mampuru is a superhero, relentless in his commitment. It’s been a pleasure working with TTO,” he added.
This development follows SMU’s historic first patent in 2024: Raloxifene Hydrochloride Hydrate Solvate, a novel compound with the potential to revolutionise treatment for postmenopausal osteoporosis and breast cancer. That breakthrough was led by Emmanuel Kiyonga, a master’s graduate in the School of Pharmacy, and marked the beginning of a new era of innovation for the university.
Together, these patents underscore SMU’s transformation into a research-intensive health sciences institution committed to addressing global health challenges through science and invention. Witika and Ngilirabanga are optimistic about the future of their research. They believe their eutectic formulation could make a major impact on drug development, particularly in the field of pain management. Further patent filings and commercialisation efforts are already underway. “This is just the beginning,” said Witika. “We’re at the forefront of something meaningful. It’s vital that inventors maintain a connection to their work—we must ensure that identity is preserved in the products we create.”
For Witika, the success is both professional and deeply personal. “Even though this is my second patent, the feeling is just as incredible. You’re reminded that you’re contributing something small but significant.” His advice to fellow academics? “Go for it. Don’t hold back.”
For Ngilirabanga, this has been a great success. “I am immensely proud of this achievement, and I am excited about the future. This is my first patent, the first of many. To my fellow academics, keep pushing. Let’s make SMU proud,” said Ngilirabanga.
Looking ahead, they hope that this achievement—along with future innovations—will encourage university leadership to recognise and support the vital role of research in shaping a better world. “These are small steps,” he said, “but they’re paving the way for greater impact on science, patients, and future scholars.”
By Tumelo Moila
by Lorato | Jun 25, 2025 | Accolades and Achievements, All News, Alumni, SMU Media, Student Media
In a momentous achievement for Sefako Makgatho Health Sciences University (SMU), Professor Deliwe Rene Phetlhu, Head of the Department of Nursing Sciences, has been awarded the prestigious National Research Foundation (NRF)’s u’Good Grant to the value of R9.1 million. Her successful proposal, selected from over 200 global submissions, is one of only 22 awarded internationally and will fund a groundbreaking project titled “Youth Mental Health in the Era of Climate Change.”
Speaking on the announcement, Professor Phetlhu expressed her elation. “I was overjoyed, particularly because I will be working with young academics, some of whom have never worked on major grants before. Being selected among the top 22 worldwide is a significant honour.”
The three-year project (2025–2027) aims to develop a culturally responsive intervention to enhance the psychological resilience and well-being of young people in South Africa, Ghana, and Tanzania. The research will be grounded in the relational well-being (RWB) theory and principles of Ubuntu, integrating culture, socio-economic contexts, and environmental stressors into its approach.
“Personally, this award affirms my commitment to impactful research,” said Phetlhu. “Professionally, it highlights the critical role nurses can play in emerging areas of health sciences. As the first line of defence in healthcare, nurses are uniquely positioned to lead research that transcends traditional boundaries.”
The project will begin by investigating youth awareness, cultural narratives, and environmental anxieties linked to climate change, before developing and piloting a targeted intervention. Innovative methodologies such as photovoice and vignettes will be employed to capture lived experiences, while technologies like RedCap will ensure secure data handling.
Funding allocation reflects the project’s community-driven ethos. Equipment such as laptops, cameras, and audio recorders will be acquired early on, but the bulk of resources are earmarked for operational costs, particularly youth engagement and travel. Administrative support across the three countries is also a key consideration.
Each project year has clear milestones:
- 2025: Understanding youth climate awareness and mental health practices across three African contexts.
- 2026: Development of an integrated, culturally grounded intervention framework.
- 2027: Implementation of a scalable model for African youth mental health resilience, potentially redefining wellbeing from a continental perspective.
“This research is urgent,” Phetlhu explains. “Globally, climate change is a daily conversation, but in Africa, the link to mental health—especially among youth—is often overlooked. From funeral queues to community gatherings, I’ve asked people their thoughts, and the lack of awareness is concerning.”
The project is proudly transdisciplinary, involving youth-centred NGOs, sociologists, environmentalists, and educational psychologists from South Africa, Ghana, and Tanzania. SMU will host the lead PhD student and two master’s candidates in later stages, while early-career researchers from the institution are included as co-investigators.
The long-term goal is to influence youth mental health policy and practice. “Mental health is becoming a global pandemic. The next generation will carry the heaviest burden of climate change, and they must be equipped with resilience and leadership skills,” Phetlhu said.
She has already initiated engagement with government and sector stakeholders. “I don’t want them to only hear about the project at the end. Their involvement from the start is essential for sustainability.”
Prof Phetlhu also extended gratitude to the SMU Grants Office. “Ms Winnie Motsatsi was phenomenal, supporting me through every step, arranging a reviewer, and accommodating my schedule. I couldn’t have done it without her.”
To fellow researchers at SMU, Phetlhu had a message of inspiration: “Take a risk. Even if it doesn’t work the first time, it’s worth trying. Surround yourself with people who share your work ethic. It might just happen.”
As the project is currently underway, Phetlhu hopes to ignite a continental dialogue on youth wellbeing and climate resilience. “Africa’s future depends on it. Let us prepare our youth to carry the baton with strength and purpose.”
By Tumelo Moila
by Lorato | Jun 25, 2025 | All News, Alumni, SMU Media, Student Media
What began as a childhood curiosity in the township of Ezinketheni has flourished into a mission-driven scientific pursuit, led by Malibongwe Ngcobo, a young researcher determined to transform healthcare through innovation in haematology. A story rooted in personal loss, faith, and academic excellence, Ngcobo’s journey reflects the spirit of resilience and visionary thinking cultivated at Sefako Makgatho Health Sciences University (SMU). With every blood sample he analyses, he brings a deeply personal commitment to excellence, redefining what it means to lead with both compassion and scientific rigour in South Africa’s evolving healthcare landscape.
After the passing of his biological mother, Ngcobo moved to Ezinketheni, Pietermaritzburg, at the age of four and was lovingly raised by his aunt and her husband, whom he honours as his parents. As the only young male in a household of girl cousins, he grew up grounded in respect, humility, and dignity.
“My foster parents instilled in me the foundational qualities of manhood, especially respect for women and others,” he shared. “My mother made sure I attended church every Sunday. Her faith in God laid the foundation for my own spiritual life, which still guides me today.”
Education was a pillar of his upbringing. His mother constantly reminded him that talent alone was insufficient—academic qualifications were the key to credibility. A cousin who regularly taught him beyond the school curriculum sparked his love for learning.
His ambition to pursue science was solidified in high school after a teacher remarked that he had the makings of a scientist. But it was the loss of his mother—who died from a haematological condition—that gave him a deep, personal motivation. “I didn’t understand what had happened to her. That drove me to learn more and help others who might face the same fate.”
In his third year at the University of KwaZulu-Natal (UKZN), Ngcobo encountered a haematology module that changed everything. “It answered questions I’d carried for years. When I learnt UKZN didn’t offer an Honours programme in Haematology, I searched for other institutions and found SMU.”
At SMU, he discovered an academically rigorous and supportive environment. “The Department of Haematological Pathology, from the secretary to the Head of Department, offered professionalism and encouragement,” he said.
For his Honours research, Ngcobo analysed 384 haematology requisition forms to assess their completeness and accuracy. The findings were striking. “Not a single form was fully completed. Even minor omissions, like missing clinician contact details, can delay critical communication and affect patient care.”
Though the data collection process was demanding, Ngcobo attributes his growth to the programme and the guidance of his supervisor, Professor Vanessa Moodley. “I learned to persevere and think critically under pressure. Professor Moodley encouraged me to view challenges creatively and holistically.”
Now serving as an Intern Biological Scientist at the National Health Laboratory Service (NHLS) at SMU, Ngcobo sees this role as a crucial step towards his goal of pursuing a PhD in Haematology. He aims to contribute innovative, evidence-based solutions that enhance diagnostics and patient care.
He is deeply committed to ethical laboratory practice and raising awareness about haematological conditions. “Every blood sample represents a life. Errors—especially during the pre-analytical phase—are unacceptable. Our role as lab professionals is critical.”
Ngcobo overcame challenges such as procrastination and self-doubt through daily discipline and the unwavering support of his department. “I began by reading just five pages a day. That small step built consistency. Believing in myself and knowing support was available made a huge difference.”
To aspiring haematologists, his message is clear: “Haematology is demanding. Opportunities are scarce. To thrive, you must be exceptional, focused, and ready to exceed expectations.”
Ngcobo’s story is not just about academic success—it is a narrative of transformation, fuelled by purpose and empathy. As he continues to build his career in haematology, he remains committed to bridging the gap between complex science and patient-centred care, ensuring that every breakthrough brings tangible benefits to those who need it most.
By Dimakatso Modise
by Lorato | Jun 25, 2025 | All News, Alumni, SMU Media, Student Media
In a proud moment for Sefako Makgatho Health Sciences University (SMU), Dr Karmishtha Maharaj was conferred with a PhD in Pharmacy during the university’s recent autumn graduation ceremony. Her achievement is not only a personal milestone but a significant contribution to advancing pharmacovigilance within the private healthcare sector, particularly in the context of HIV treatment in South Africa.
Now 39 years old, Dr Maharaj is currently based at Ampath Laboratories in Centurion, where she serves as a Pharmacogenomics Specialist. Her professional journey with Ampath spans over 13 years, beginning in 2011 as a Phlebotomy Facilitator. Originally from Newcastle in KwaZulu-Natal, Maharaj’s career has been deeply shaped by her upbringing in a close-knit family and an enduring desire to bridge patient care and pharmaceutical science.
“My interest in medicine began early,” she reflects. “From weekends volunteering at a private hospital to shadowing my uncle at his pharmacy, I was always drawn to helping others. I first trained as a nurse and later transitioned into pharmacy, blending the clinical and pharmaceutical sides of patient care.”
Maharaj’s doctoral research, conducted through SMU’s School of Pharmacy, focused on the use of routine laboratory tests as early indicators of adverse drug reactions (ADRs) in patients on Highly Active Antiretroviral Therapy (HAART). Her study, conducted at a major private HIV treatment practice in Pretoria, sought to address a critical gap in South Africa’s pharmacovigilance data, particularly within the under-researched private healthcare sector.
She strongly believes laboratory-based monitoring should become a standard in ADR surveillance. “It enables early detection of toxicity before symptoms appear, allowing timely interventions. This approach not only improves patient safety and adherence but fills major gaps in traditional pharmacovigilance, especially when managing complex cases involving multiple medications.”
Despite the private sector being relatively well-equipped, with access to electronic health records and accredited laboratories, Maharaj points out that systemic challenges remain. “There’s no coordinated pharmacovigilance framework in private care. Proactive monitoring is still underutilised, and pharmacogenomics testing is limited due to cost and lack of awareness.”
Her study reviewed 267 patient files from a private HIV clinic in Pretoria. Elevated creatinine and liver enzymes served as early warning signs of renal and hepatic toxicity. She observed that patients on concomitant medications had heightened risks, and that ART changes were most commonly associated with drugs like efavirenz and lopinavir.
“My research offers valuable insights that can contribute to national health policy,” she says. “It provides a model for integrating lab data into national pharmacovigilance frameworks, updating HIV treatment guidelines, and improving surveillance beyond clinician reporting.”
She is also eager to expand the research to public health settings and rural areas. “We need to ensure the research represents the broader HIV population. Exploring regional differences and building scalable, risk-based models could strengthen provincial and national responses to HIV care.”
Looking ahead, Maharaj envisions several research paths, including prospective studies, cost-effectiveness analysis of lab-based surveillance, and the feasibility of implementing pharmacogenomic testing and therapeutic drug monitoring locally.
She also hopes to see her findings incorporated into national medical training and treatment guidelines. “Empowering healthcare providers with these tools through education would support a more predictive, personalised approach to care.”
Completing a PhD while working full-time was no small feat. “It required planning, discipline, and self-care. My support system—family, mentors, friends—was essential. There were moments of doubt and setbacks, but also incredible breakthroughs that reminded me why this work matters.”
Now that she has earned her PhD, Maharaj plans to continue blending academic research with public engagement. “I want to raise awareness around drug safety and help integrate personalised medicine into routine care.”
She hopes her legacy is one of improved patient safety and inspired future researchers. “For young women from underrepresented backgrounds, I say: believe in your potential. Your voice matters, and your journey can change lives.”
Summing up her journey, Maharaj shares, “The rewarding challenge of pioneering new paths. As Elizabeth Blackwell said, ‘It is not easy to be a pioneer – but oh, it is fascinating!’”
By Tumelo Moila
by Lorato | Jun 25, 2025 | All News, Alumni, SMU Media, Student Media
At just 25, Clement Mphethi is helping redefine what is possible for young South Africans who dare to dream beyond their circumstances. Graduating summa cum laude with a Bachelor of Science Honours in Physics from Sefako Makgatho Health Sciences University (SMU), Mphethi’s journey is one of resilience, intellect, and inspiration — a testament to the power of education to rewrite history.
Originally from Burgersfort, Limpopo, Mphethi is the first in his family to attend university. “This achievement carries emotional weight,” he says. “It’s a tribute to the struggles of those who came before me and a reminder that determination can break generational barriers.”
Mphethi’s fascination with Physics started early. “Physics has always fascinated me. It’s the pursuit of truth, the language of the universe,” he explains. But his motivation was deeply personal. “My parents, despite their intelligence, never had the opportunity to study further. I pursued this degree for them and for everyone who never had the chance.”
Graduating with top honours was not merely a personal milestone — it was a deeply meaningful accomplishment born of sacrifice, discipline and vision. “In trying to understand the universe, I came to understand my own mind — its limits, potential, and ability to grow through adversity and purpose,” he reflects.
Now self-employed as a freelance data scientist, Mphethi applies machine learning, data analysis and statistical modelling to solve real-world problems for clients across industries. His interest in data science stems from the interdisciplinary nature of modern physics. “I studied programming languages like Python, SQL, JavaScript and tools like Power BI and Excel outside of my academic studies, driven by an interest in how they can be applied alongside physics to address real-world problems.”
During his Honours year, Mphethi delved into Quantum Physics and Statistical Mechanics, two fields that reshaped his worldview. “Quantum forced me to rethink everything. It showed me that uncertainty isn’t weakness, but part of nature. Statistical Mechanics helped me understand how order arises from chaos.”
His research focused on dye-sensitised solar cells (DSSCs), exploring how different electrolyte deposition techniques impact performance and sustainability. “Using a solar simulator, I discovered that doctor-blading achieved the highest efficiency,” he notes. “The experience taught me the importance of precision, persistence, and thinking about the environmental impact of our work.”
The journey was not without challenges. “Inconsistent results, mental fatigue, and deadlines were constant obstacles,” he recalls. “But support from my supervisors and my classmate Lebogang Motau, who also graduated summa cum laude, kept me going. That shared journey meant everything.”
Mentorship was another pillar of his success. Professor Enoch Sithole, his supervisor, left a lasting impression. “He was more than a lecturer. He challenged us because he believed in us. He taught that discipline is a form of care.”
Beyond academics, Mphethi stepped into leadership as class representative. “I learnt how to represent others, communicate effectively, and lead with empathy,” he shares.
Looking to the future, he is focused on quantum technologies and renewable energy. “Quantum computing and green tech are urgent and full of potential. That’s where I want to contribute. Physics helps us confront global challenges like climate change. It teaches us to ask the right questions.” Mphethi is also passionate about science communication. “Physics isn’t just equations. It’s about improving lives. We need to tell that story more clearly.”
His advice to aspiring students is clear: “Stay disciplined, manage your time, and don’t fear failure. Growth comes through struggle.”
As he continues his journey in research and applied science, Mphethi’s story stands as a beacon for a new generation. “I carry not just ambition, but the hopes of a family who never had these chances. My journey proves that with purpose and perseverance, even the toughest obstacles can be overcome.”
From the quiet hills of Limpopo to the dynamic frontiers of quantum physics, Mphethi is not just rewriting his own story — he’s helping rewrite South Africa’s scientific future.
By Tumelo Moila
