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SMU graduate develops innovative antimicrobial-use assessment tool

SMU graduate develops innovative antimicrobial-use assessment tool

Sefako Makgatho Health Sciences University (SMU) is advancing research into antimicrobial resistance through the doctoral work of Dr Nishana Ramdas, who graduated with a PhD in Pharmacy at the university’s 2026 Spring Graduation Ceremony. Her doctoral research addresses a critical public health challenge by examining the behavioural factors that influence antibiotic use among patients in South Africa’s primary healthcare system.

 

SMU graduate develops innovative antimicrobial-use assessment tool (2)Titled Development and Validation of a Community Anti-Microbial Use Scale (CAMUS) for Use at Primary Health Care Level in South Africa, the research developed and validated a tool to help identify misconceptions, social influences and behavioural patterns associated with inappropriate antibiotic use.

 

Antimicrobial resistance (AMR) occurs when microorganisms develop the ability to resist medicines designed to treat infections. Inappropriate antibiotic use contributes to this growing global threat, making responsible medicine use and effective antimicrobial stewardship essential to protecting public health.

 

Dr Ramdas’s research involved a sequential mixed-methods approach, including a scoping review, instrument development, pilot testing and psychometric validation. The study surveyed 1,283 adult patients across 25 public healthcare facilities in Gauteng and Limpopo.

 

The findings revealed significant misconceptions about antibiotics. More than three-quarters of participants (76.5%) believed antibiotics could cure colds and flu, while 22.8% reported obtaining antibiotics without a prescription. Among those reporting non-prescribed use, community pharmacies were the primary source, accounting for 81.7%.

 

The research also found that non-prescribed antibiotic use was significantly associated with inadequate health literacy, misconceptions about antibiotics and permissive social and behavioural norms. Non-prescribed use was more prevalent in high-density peri-urban township settlements (36.3%) than in rural areas (16%).

 

These findings highlight that inappropriate antibiotic use extends beyond gaps in knowledge and is also influenced by social practices, health literacy and community expectations.

 

SMU graduate develops innovative antimicrobial-use assessment tool (1)The 30-item CAMUS instrument measures five domains: understanding of antibiotics; social and behavioural norms; non-prescribed use and community practices; understanding of antimicrobial resistance; and attitudes and beliefs influencing patient demand for antibiotics. The validated tool offers a structured approach to identifying factors that may inform targeted, patient-centred antimicrobial stewardship interventions.

 

Dr Ramdas’s achievement builds on an extensive career in pharmacy, public health and pharmaceutical services. She continues to support the National Department of Health (NDoH) in the coordination and implementation of the national Central Chronic Medicine Dispensing and Distribution (CCMDD) programme, which aims to improve access to chronic medicines for patients in South Africa. Her professional experience also includes pharmaceutical systems strengthening and healthcare workforce training.

 

In addition to her ongoing work supporting the national CCMDD programme, Dr Ramdas was appointed as an extraordinary lecturer in the Department of Pharmacology at the University of Pretoria in 2026. She also contributes to postgraduate research co-supervision, curriculum development and university teaching.

 

Her doctoral research has contributed to five first-author publications in international peer-reviewed scientific journals, covering community antibiotic use, behavioural influences and the development and validation of CAMUS. These contributions support evidence-based approaches to strengthening antimicrobial stewardship and improving appropriate antibiotic use.

 

The study recommends moving beyond awareness campaigns towards community-based interventions that address health literacy and social influences. It also highlights opportunities to improve communication between healthcare professionals and patients, strengthen oversight of access to non-prescribed antibiotics, and integrate CAMUS into national surveillance strategies.

 

Through Dr Ramdas’s doctoral achievement, SMU reinforces its commitment to innovative research, professional training and evidence-based solutions to public health challenges. The work shows how research in South Africa’s health sciences sector can inform interventions to improve patient care and address antimicrobial resistance.

By Tumelo Moila

SMU graduate advances diabetes research through doctorate

SMU graduate advances diabetes research through doctorate

Sefako Makgatho Health Sciences University (SMU) lecturer Dr Mashudu Nemukula has earned his Doctor of Philosophy (PhD) in Biochemistry at the university’s 2026 Spring Graduation Ceremony, marking a major milestone in his academic career and advancing research on diabetes and atherosclerotic cardiovascular disease.

 

SMU graduate advances diabetes research through doctorate (1)Dr Nemukula, a lecturer in Clinical Biochemistry and Healthcare Biotechnology in SMU’s Department of Biochemistry and Biotechnology, investigated the relationship between low-density lipoprotein (LDL) subclasses and the burden of atherosclerosis among black South African patients with Type 2 diabetes mellitus (T2DM). His thesis was titled “LDL subclasses and atherosclerosis burden in black South African Type II diabetic patients at Dr George Mukhari Academic Hospital”.

 

His research combined a systematic review and meta-analysis, a hospital-based cohort study, and nuclear magnetic resonance (NMR)-based serum metabolomic and lipidomic profiling. The study sought to improve understanding of lipid abnormalities and the metabolic changes associated with diabetes, which can increase the risk of cardiovascular complications.

 

The findings highlighted the prevalence of lipid abnormalities among South Africans with hyperglycaemia and identified treatment non-adherence as an independent factor associated with elevated LDL cholesterol. The research also characterised a metabolic signature associated with T2DM among people of black South African ancestry, identifying changes in amino acid, energy and gut microbial metabolism that may inform future precision-medicine approaches.

 

“Achieving my PhD is more than an academic milestone; it is a testament to perseverance, faith, dedication, and God’s grace throughout my journey. As Philippians 4:13 reminds us, ‘I can do all things through Christ who strengthens me.’ This scripture reflects the strength and determination that carried me through the challenges and sacrifices of this journey. I hope this milestone inspires future scientists and contributes to meaningful research that improves healthcare in South Africa,” said Dr Nemukula

 

The study further examined disruptions in lipoprotein and LDL-cholesterol metabolism in relation to endothelial dysfunction, oxidative stress, inflammation and atherosclerotic cardiovascular disease. The study used aortic pulse wave velocity to assess vascular stiffness, providing additional insight into cardiovascular risk.

 

SMU graduate advances diabetes research through doctorate (2)Dr Nemukula’s achievement builds on a career spanning more than a decade in higher education, laboratory demonstration, clinical research and academic administration. He has been a permanent lecturer at SMU since December 2021, where he coordinates undergraduate modules, teaches biochemistry and supervises or co-supervises Honours, master’s and Master of Medicine research projects.

 

He obtained his MSc in Biochemistry cum laude from SMU in 2019, following undergraduate studies in Biochemistry, Microbiology and Biochemistry-related disciplines at the University of Limpopo and the University of Venda. Between October 2024 and April 2025, he undertook an international research placement at the International Centre for Genetic Engineering and Biotechnology in New Delhi, India, focusing on NMR spectroscopy, metabolomics, and protein-DNA interaction techniques.

 

During his doctoral candidature, Dr Nemukula published four research articles, with a further manuscript under review, contributing to the growing body of knowledge on metabolic health and cardiovascular disease.

 

His achievement reflects SMU’s commitment to advancing scientific research, developing skilled health-sciences professionals and supporting evidence-based approaches to healthcare challenges. Through research, teaching, and postgraduate supervision, Dr Nemukula continues to contribute to the university’s academic mission and strengthen knowledge relevant to diabetes and cardiovascular health in South Africa.

By Tumelo Moila

SMU academic tackles workplace burnout through doctoral research

SMU academic tackles workplace burnout through doctoral research

Sefako Makgatho Health Sciences University (SMU) academic Dr Veena Abraham has earned a PhD in Pharmacy through a collaborative doctoral programme with the University of Stirling in Scotland, highlighting the need for institutional policies that address mental health and burnout among university academics.

 

SMU academic tackles workplace burnout through doctoral research (1)Awarded in 2026, her doctorate focused on developing and pre-testing an evidence-informed mental health promotion policy for academic staff at a historically disadvantaged South African university. Her research examined how workloads, organisational culture, leadership practices and limited institutional support affect staff wellbeing in higher education.

 

The study found that 49% of surveyed academic staff screened positive for severe psychological distress, while 27% reported high levels of burnout. The institutional survey involved 157 respondents and revealed that fewer than one-third felt comfortable disclosing mental health concerns, while more than half expressed dissatisfaction with institutional support.

 

“These findings highlight the importance of recognising mental health and burnout as workplace concerns that require institutional attention. Universities need to understand how working conditions, leadership practices and organisational culture affect academic staff and their ability to thrive professionally,” said Dr Abraham.

 

The findings highlight the scale of the challenge facing universities. As the study concludes, “Academic staff mental health is shaped by interconnected individual, organisational and structural factors.” This points to the need for institutions to look beyond individual wellness initiatives and address the workplace conditions contributing to psychological distress.

 

Dr Abraham’s research used a four-phase, mixed-methods approach, combining a systematic review of workplace mental health interventions, an institutional survey, qualitative interviews and a focus group, followed by policy development and stakeholder pre-testing. This enabled her to integrate international research evidence with the experiences and needs of academic staff in the South African higher education context.

 

“The research was driven by the need to develop a practical, evidence-informed response that reflects the realities of academic life in South Africa. Policies must be grounded in research and shaped by the experiences of the people they are intended to support,” she said.

 

The resulting policy framework addresses workload management, leadership accountability, psychological safety, access to mental health support and organisational culture. Stakeholder pre-testing indicated that the proposed policy was acceptable, although institutional readiness and implementation capacity remained important considerations.

 

SMU academic tackles workplace burnout through doctoral research (2)Emphasising the need for sustainable institutional action, the study concludes that “sustainable mental health promotion requires coordinated institutional action addressing the underlying conditions contributing to distress and burnout.”

 

The findings therefore support a shift towards approaches that recognise staff wellbeing as an organisational responsibility rather than an issue for individuals to manage alone.

 

Dr Abraham’s interest in workplace wellbeing developed from her earlier research into patient safety culture at Dr George Mukhari Academic Hospital, which she completed for her Master of Pharmacy degree, awarded cum laude in 2017 from SMU. This work informed her broader interest in how organisational environments, leadership and workplace practices influence professionals’ experiences.

 

With more than 15 years of experience in health sciences education, Dr Abraham lectures in SMU’s Department of Pharmacology and Therapeutics, teaching across health sciences programmes, including medicine and dentistry. Her academic contributions also include curriculum development, assessment, postgraduate supervision and mentorship.

 

She received the SMU Teaching Excellence Award in 2022 and has published research on workplace mental health, patient safety and healthcare practice. Her scholarly work reflects a commitment to connecting research evidence with practical institutional challenges.

 

“Creating healthier academic environments requires a sustained commitment to supportive leadership, open communication and policies that can be implemented in practice. I hope this research contributes to conversations about how universities can better protect and promote the wellbeing of their academic staff,” said Dr Abraham.

 

Dr Abraham’s achievement reinforces SMU’s commitment to research that responds to pressing challenges in education and the health sciences. By developing a contextually responsive mental health promotion policy, her research provides a foundation for universities seeking to strengthen workplace support, improve organisational practices and create healthier academic environments.

By Tumelo Moila

SMU PhD graduate advances antimicrobial stewardship through research

SMU PhD graduate advances antimicrobial stewardship through research

Sefako Makgatho Health Sciences University (SMU) continues to advance evidence-based healthcare through research that addresses critical public health challenges, as demonstrated by pharmacist and public health researcher Dr Tiyani Milta Maluleke, whose doctoral study explored strategies to promote responsible antibiotic use in rural South Africa.

 

SMU PhD graduate advances antimicrobial stewardship through researchMaluleke earned her PhD in Public Health Pharmacy during SMU’s annual Spring Graduation Ceremony, marking a significant milestone in a career spanning more than 22 years across South Africa’s public and private healthcare sectors. Her achievement reflects SMU’s commitment to developing skilled healthcare professionals and producing research that informs healthcare policy and practice.

 

Her doctoral research, titled Strategies to limit inappropriate purchasing of antibiotics without a prescription in a rural province, South Africa, examined factors influencing antibiotic access and identified opportunities to strengthen antimicrobial stewardship and patient education in underserved communities.

 

Antimicrobial resistance (AMR) occurs when microorganisms develop the ability to resist medicines used to treat infections. Inappropriate antibiotic use contributes to this growing public health challenge, making responsible dispensing, patient education and accessible healthcare essential.

 

Maluleke’s mixed-methods study engaged community pharmacy personnel and patients to better understand antibiotic access, healthcare-seeking behaviour, and opportunities to improve antimicrobial stewardship. The research highlighted the importance of practical, collaborative interventions that support both patients and healthcare professionals.

 

The findings identified previous antibiotic use and long clinic waiting times as factors influencing healthcare-seeking decisions. Patients also strongly supported pharmacist-led antibiotic education, highlighting an opportunity to strengthen community pharmacies’ contribution to public health.

 

“These findings highlight the need for antimicrobial stewardship interventions that address both patient behaviour and the challenges within the healthcare system,” explained Dr Maluleke.

 

The study recommends strengthening community pharmacists’ involvement in patient education, appropriate referrals, quality improvement initiatives and collaboration with prescribers. It also advocates for appropriately regulated pathways to expand pharmacists’ clinical responsibilities and improve patient access to appropriate care.

 

“Community pharmacists are well positioned to support antimicrobial stewardship through protocol-led management of selected infections, patient education, referral and collaboration with prescribers,” said Dr Maluleke.

 

SMU PhD graduate advances antimicrobial stewardship through researchMaluleke’s research reinforces SMU’s mission to transform health services through excellence and innovation. By supporting postgraduate research exploring challenges affecting underserved communities, the university helps generate evidence that can inform policy, strengthen professional practice and improve patient outcomes.

 

Her achievement also builds on a longstanding commitment to pharmaceutical practice and research. Maluleke completed her Master of Public Health at SMU in 2019 and obtained her Bachelor of Pharmacy from MEDUNSA in 2003. Her scholarly contributions include eight publications in international peer-reviewed journals, three editorials and co-author contributions to five additional publications.

 

Beyond her professional career, she is the founder and minister of Ntshembo Healing Ministry, where she promotes community empowerment, mentorship and holistic wellbeing. As a motivational speaker and organisational leader, she seeks to bridge scientific knowledge, public service and faith-based leadership.

 

Through graduates such as Maluleke, SMU demonstrates the value of health sciences education and research in addressing South Africa’s healthcare priorities. Her doctoral work highlights the university’s contribution to developing research-informed professionals equipped to strengthen pharmacy practice, promote responsible medicine use and support better healthcare outcomes.

By Tumelo Moila

SMU research highlights childhood trauma’s lasting impact

SMU research highlights childhood trauma’s lasting impact

Dr Bonolo Mmereki has earned a Doctor of Philosophy (PhD) in Public Health from Sefako Makgatho Health Sciences University (SMU), following research highlighting the lasting impact of childhood trauma on young adults’ mental health in South Africa.

 

SMU research highlights childhood trauma’s lasting impact (1)

Awarded during SMU’s annual Spring Graduation Ceremony in September 2026, her qualification marks a significant milestone in her public health career and advances research into childhood trauma, mental health screening and interventions at the primary healthcare level.

 

Her doctoral study, titled The impact of childhood trauma on the mental health of young adults: a mixed method study among clinic attendees in Moretele Sub-health District, investigated the relationship between adverse childhood experiences and mental health outcomes among young adults aged 18 to 35 attending healthcare facilities in Moretele, North West.

 

Childhood trauma is a significant public health concern, with consequences that can persist long after the initial experience. Mmereki’s research examined how these experiences affect mental health, relationships, emotional wellbeing and everyday functioning, highlighting the need for early identification and appropriate support within healthcare services.

 

Using a convergent mixed-methods design, the study combined quantitative screening with qualitative interviews. Data were collected from 380 participants across five healthcare facilities, while in-depth interviews were conducted with 14 participants to explore their experiences of childhood trauma. The research used standardised questionnaires to screen for childhood trauma, depressive symptoms and anxiety.

 

The findings showed that 9% of participants had experienced childhood trauma, while 12% presented with depressive symptoms and 8% showed signs of anxiety. The qualitative findings further revealed the complex and enduring effects of traumatic experiences, including nightmares, social isolation, anger, and challenges affecting academic performance and personal relationships.

 

SMU research highlights childhood trauma’s lasting impact (2)

Thirteen themes and 17 sub-themes emerged from the qualitative data. These included different forms of trauma, the impact and consequences of traumatic experiences, triggers, perceptions that justice had not been served, the need for ongoing post-trauma support, and the development of coping mechanisms.

 

A key outcome was the development of a protocol for healthcare workers, along with recommendations and strategies to strengthen childhood trauma screening, policy development, and mental health services in primary healthcare facilities in Moretele.

 

The study has also contributed to academic knowledge through publications in international and local journals, demonstrating the potential of community-based research to inform healthcare practice and policy.

 

Mmereki’s achievement builds on a professional nursing career spanning approximately a decade, with experience in HIV/AIDS care, non-communicable diseases and public health. She holds a Bachelor of Nursing Science degree from North-West University and a Master of Public Health from SMU. Her work also includes adolescent and youth-friendly services, reflecting her commitment to improving access to responsive healthcare for young people.

 

Her research aligns with SMU’s mission to advance health services through excellence and innovation, particularly through education, research and the development of evidence-based approaches to healthcare challenges. By investigating the long-term effects of childhood trauma and proposing practical interventions, her work contributes to efforts to strengthen mental health support within primary healthcare settings.

 

Mmereki’s doctoral achievement reflects the role of postgraduate research in addressing pressing public health challenges and generating knowledge that can inform policy, improve clinical practice, and support community wellbeing.

By Tumelo Moila

 

 

Global rankings highlight SMU’s research and innovation strengths

Global rankings highlight SMU’s research and innovation strengths

Sefako Makgatho Health Sciences University (SMU) has reaffirmed its place on the global higher education stage, with the 2027 Times Higher Education (THE) World University Rankings highlighting significant gains in industry engagement, a strengthening research environment and sustained international competitiveness.

 

SMU on the Global StageThe latest rankings, which assessed 2,297 universities across 118 countries and territories, position SMU among internationally recognised institutions contributing to the advancement of knowledge, research and innovation.

 

As South Africa’s specialist health sciences university, SMU continues to compete with established medical and health sciences institutions internationally, reinforcing its growing relevance in an increasingly competitive global academic landscape.

 

A key highlight of the 2027 results is SMU’s strong improvement in industry engagement, with its performance score rising from 19.2 to 29.4, a 10.2-point gain. This is the university’s greatest year-on-year improvement and reflects encouraging progress in an area that measures knowledge transfer, innovation and engagement with industry.

 

The university’s Research Environment score also improved from 11.1 to 14.6, signalling positive momentum in strengthening the institutional conditions that support research productivity, reputation and investment.

 

International Outlook remains SMU’s highest-performing indicator at 50.1, underscoring its competitive position in international academic engagement and research collaboration.

 

Equally encouraging is SMU’s Research Quality score of 41.9, which compares favourably with established specialist medical universities in China, Poland and Japan within the same global ranking band. This performance demonstrates the university’s capacity to produce research that competes within the international health sciences landscape.

 

Acting Vice-Chancellor and Principal Professor Dini Mawela describes the results as an affirmation of SMU’s academic potential and a key foundation for accelerating institutional excellence.

 

“Our ambition has never been simply to occupy a position on a global ranking table. It is to build a university whose knowledge, discoveries and graduates make a meaningful difference to healthcare and society. These results affirm that SMU possesses the research capability, international relevance and institutional potential to compete on the world stage. The significant improvement in industry engagement is particularly encouraging because it speaks to our ambition to translate academic knowledge into innovation and societal impact. We are building an institution that is not merely participating in global higher education but is determined to shape the future of health sciences in Africa and beyond.”

 

Acting Director: Advancement and Communications, Tshimangadzo Mphaphuli, says the results reinforce SMU’s positioning as a credible and competitive institution within the global health sciences education landscape.

 

“The strength of the SMU brand lies not simply in where we are ranked, but in what we represent and the value we deliver. For prospective students, our University represents an opportunity to pursue a future in the health sciences. For our partners and stakeholders, it represents an institution with growing research capabilities, international connections and opportunities for meaningful collaboration. Our global presence, coupled with measurable progress in key performance areas, gives us a compelling story to tell with confidence. We want every student, parent, alumnus, industry partner and member of the public to recognise SMU as a university of choice, whose relevance and contribution extend far beyond its campus.”

 

Mawela further emphasises that the university will use the findings to sharpen its strategic priorities, particularly research investment, postgraduate development, international partnerships and academic excellence.

 

While SMU is positioned in the 1401–1600 global band for 2027, up from 1201–1500 in 2026, underlying performance indicators reveal key institutional strengths and opportunities for continued advancement.

 

For SMU, the message extends beyond rankings: its growing research capability, international competitiveness and strengthening innovation ecosystem provide a foundation for advancing its contribution to health sciences education, research and healthcare development.