Biochemistry Research Areas
BIOCHEMISTRY RESEARCH AREAS
Prof Alfred Mogale: Protein chemistry The research group involves two different areas:
| |
Dr Sechene Stanley Gololo: Phytochemistry
| |
Ms Emelinah Mathe: Cancer biology There are several limitations with regard to traditional cytotoxic anticancer drugs, they kill cells that divide rapidly and bring about high incidence of adverse effects, e.g myelo-suppression and immunosuppression. In light of these limitations, targeted anticancer agents are being developed in recent years in orde to find safe treatment for cancer drug therapy. Our principal aims:
| |
Mrs Sebolaishi Makhubela: Protein chemistry Proteins are an integral part of all cells, from microorganisms to plants and animals. Their roles are diverse and include: transportation of molecules, catalysis of reactions, structural proteins, they form part of the defense system, they are receptors for ligands and they act as hormones. Our research focuses on the purification and characterization of proteins from various sources. We purify proteins using different fractionation and chromatographic methods, followed by their characterization. Knowledge of the characteristics of these proteins assists us in understanding their structures as well and their functions. | |
Mr Hodi Ananias Kgopa: Gene expression Our research laboratory investigates markers using molecular techniques; RT-PCR, gene expression, sequencing in two different areas:
|